Studies of Chemical Rates Processes by Means of Size and Charge Resolved 2D-NMR

通过尺寸和电荷分辨 2D-NMR 研究化学速率过程

• 批准号: 9222590
• 负责人: Charles Johnson
• 金额: $ 38.05万
• 依托单位: University of North Carolina at Chapel Hill
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-02-15 至 1996-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9222590&HistoricalAwards=false
• 关键词: Studies; Chemical; Rates; Processes; Means

In this project, supported by the Physical Chemistry Program of the Chemistry Division, Prof. C. Johnson of the University of North Carolina at Chapel Hill will conduct research in the area of diffusion-ordered two-dimensional nuclear magnetic resonance spectroscopy. This research will be devoted to the development of techniques and instrumentation, and their applications to chemical exchange effects, binding equilibria involving surfactants and macromolecules, and micelles and micellanes. Work will also be done on the continued development of mobility-ordered two-dimensional nuclear magnetic resonance spectroscopy with special emphasis on electrokinetic studies and data analysis for the diffusion and mobility of vesicles ranging in size from 50 to 200 nanometers. %%% The relaxation rates observed in nuclear magnetic resonance spectra of condensed media are affected by frictional effects determined by the sizes and shapes of molecules as they undergo translational and reorientational motions in the medium. The recently developed technique of diffusion-ordered two-dimensional nuclear magnetic resonance spectroscopy allows the identification of molecular components of mixtures and the simultaneous characterization of the sizes of aggregates and other structures present. Using a variation of this technique, mobility-ordered two-dimensional nuclear magnetic resonance spectroscopy, one is able to identify and determine the mobilities of ions in condensed media. The research by Professor Johnson serves to improve on these methods and extend them into the three dimensional domain.

在这个项目中，由物理化学计划支持， 化学系教授C。大学的约翰逊 位于查佩尔山的北卡罗来纳州将在 扩散有序二维核磁共振区 共振光谱学 这项研究将致力于 技术和仪器的发展， 应用于化学交换效应、结合平衡 包括表面活性剂和大分子，以及胶束， 胶束。 还将继续开展工作， 迁移率有序二维核 磁共振波谱学，特别强调 电动力学研究和数据分析的扩散和 大小在50到200纳米范围内的囊泡的流动性。 %%% 核磁共振中观察到的弛豫率 压缩介质的光谱受摩擦效应的影响 由分子的大小和形状决定 介质中的平移和再定向运动。 的 最近发展的扩散有序技术 二维核磁共振光谱学允许 混合物分子组分的鉴定和 同时表征聚集体的尺寸， 其他结构存在。 使用这种技术的变体， 迁移率有序二维核磁共振 光谱学，人们能够识别和确定 离子在凝聚介质中的迁移率 所做的研究 约翰逊教授致力于改进这些方法， 进入三维空间。