Electrophoretic NMR with Toroid Cavity Probes

使用环形腔探头的电泳 NMR

• 批准号: 9708228
• 负责人: Charles Johnson
• 金额: $ 14.55万
• 依托单位: University of North Carolina at Chapel Hill
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-07-15 至 1999-10-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9708228&HistoricalAwards=false
• 关键词: Electrophoretic; NMR; Toroid; Cavity; Probes

This research project, which is supported by the Analytical and Surface Chemistry Program and the Office of Multidisciplinary Activities, focuses on the development of a toroid cavity probe for use as an NMR detector for electrophoresis. Professor Johnson and his student at the University of North Carolina at Chapel Hill will construct a toroid cavity probe, characterize its performance as an electrophoresis detector, and write programs necessary for the handling of data. This instrument will be able to detect all components in a mixture and the analysis time will be less than 100 msec. These measurements will provide information about the chemical interactions that occur in ordered media, such a micelles. This information will be useful in understanding the behavior of these materials as pseudo-stationary phases in many separation processes. In this project toroid cavity detectors will constructed and designed for use in nuclear magnetic resonance spectroscopy to permit studies of electrophoretic processes. In addition to the construction of this new detector for nuclear magnetic resonance spectroscopy, programs will be written to acquire and handle the data produced in these experiments. Analysis of all components in a mixture will be possible and the analysis time will be less than 100 milliseconds. This new instrumental capability will have applications ranging from microscopic imaging to the study of the interactions that occur in high pressure fluids.

该研究项目由分析和表面化学计划和多学科活动办公室支持，重点是开发一种环形腔探针，用于电泳的核磁共振检测器。约翰逊教授和他在北卡罗来纳大学教堂山分校的学生将构建一个环形腔探针，描述其作为电泳探测器的性能，并编写处理数据所需的程序。该仪器将能够检测混合物中的所有成分，分析时间将小于100毫秒。这些测量将提供有关在有序介质（如胶束）中发生的化学相互作用的信息。这些信息将有助于理解这些材料在许多分离过程中作为伪固定相的行为。在这个项目中，环形腔探测器将被建造和设计用于核磁共振波谱，以允许电泳过程的研究。除了建造这个新的核磁共振波谱探测器外，还将编写程序来获取和处理这些实验中产生的数据。分析混合物中的所有成分将成为可能，分析时间将少于100毫秒。这种新的仪器功能的应用范围从微观成像到高压流体中发生的相互作用的研究。