Mechano-adaptation in Osteogenesis Imperfecta

成骨不全的机械适应

• 批准号: 461541
• 负责人: Willie Bettina M
• 金额: $ 63.25万
• 依托单位: Shriners Hospital for Children (Montral)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-03-01 至 2027-03-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=461541&lang=en
• 关键词: Bone; Mechanical Forces; Osteocytes; Osteogenesis Imperfecta

Osteogenesis imperfecta is a rare disorder that results in frequent fractures and often requires orthopedic interventions. Our clinical studies show that the periosteal circumference is consistently low in children with osteogenesis imperfecta. A lack of

骨生成障碍是一种罕见的疾病，导致频繁骨折，往往需要矫形干预。我们的临床研究表明，骨膜周长始终是低的儿童成骨不全。缺乏