Targeting Hypusine signaling: an opportunity to counter pulmonary vascular remodelling in pulmonary arterial hypertension

靶向Hypusine信号传导：对抗肺动脉高压肺血管重塑的机会

• 批准号: 467948
• 负责人: Bonnet Sbastien
• 金额: $ 61.58万
• 依托单位: Universit Laval
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-09-01 至 2027-09-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=467948&lang=en
• 关键词: Pulmonary Hypertension, Vascular Disease

Patients with pulmonary arterial hypertension have a dysfunction of the cells constituting the wall of their arteries in the lungs. Like cancer cells, PAH cells are characterized by exaggerated capacity to multiply and resistance to death resulting in a p

肺动脉高压患者的肺动脉壁细胞功能紊乱。像癌细胞一样，多环芳烃细胞的特点是增殖能力和抵抗死亡，导致p