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Molecular basis for vascular remodeling in pulmonary arterial hypertension

Molecular basis for vascular remodeling in pulmonary arterial hypertension
肺动脉高压血管重塑的分子基础
批准号:
237010
负责人:
Bonnet Sbastien
金额:
$47.15万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-09-01 至 2016-09-01

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中文摘要
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英文摘要
Pulmonary hypertension is a disease of the lung blood vessels characterized by a sustained proliferation of the cells composing the lung blood vessel wall. This proliferation will decrease blood perfusion and thus blood oxygenation. Despite new therapeuti
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Exploring the Interplay between Metabolic and Epigenetic Signalling Pathways to Regulate Neointima Hyperplasia
  • 批准号:
    477700
  • 项目类别:
    Operating Grants
  • 资助金额:
    $81.37万
  • 财政年份:
    2023
  • 负责人:
    Bonnet Sbastien
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Targeting Hypusine signaling: an opportunity to counter pulmonary vascular remodelling in pulmonary arterial hypertension
  • 批准号:
    467948
  • 项目类别:
    Operating Grants
  • 资助金额:
    $61.58万
  • 财政年份:
    2022
  • 负责人:
    Bonnet Sbastien
  • 依托单位:
The anti-oxidative DNA damage protein MTH1, the novel pulmonary hypertension Achilles heel.
Replication stress and pulmonary hypertension: Role for checkpoint kinase 1
  • 批准号:
    368035
  • 项目类别:
    Operating Grants
  • 资助金额:
    $51.83万
  • 财政年份:
    2017
  • 负责人:
    Bonnet Sbastien
  • 依托单位:
海外基金