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Using Unique Methods in Flow Virometry to Identify and Study Proteins on the HIV Surface.

Using Unique Methods in Flow Virometry to Identify and Study Proteins on the HIV Surface.
使用流式病毒测定中的独特方法来识别和研究 HIV 表面的蛋白质。
批准号：
472762
负责人：
Guzzo Christina R
金额：
$21.86万
依托单位：
University of Toronto Scarborough (ON)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2022
资助国家：
加拿大
项目状态：
未结题
起止时间：
2022-09-01 至 2025-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=472762&lang=en
关键词：
Cd4+ T Cels Clinical And Lab-Adapted Hiv Isolates Flow Cytometry Flow Virometry Hiv Envelope Glycoprotein (Gp120) Human Immunodeficiency Virus - Type 1 (Hiv-1) Peripheral Blood Mononuclear Cells (Pbmc) Virion-Incorporated Proteins Virus Attachment

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中文摘要
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英文摘要
The global burden of HIV/AIDS remains one of the greatest scientific and public health challenges of our time, with more people infected with HIV today across the globe than the entire population of Canada. Progress in this field requires a better underst
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Using unique methods in flow virometry to discover new proteins on the HIV surface and their impact on HIV infection.
The incorporation of human proteins into the external HIV envelope: using novel tools to phenotype viral surfaces and identify new antiviral targets.
Molecular mechanism of HIV blockade by a novel antiviral chemokine, XCL1.
The effect of HIV infection and anti-retroviral therapy on expression levels of the IL-27 cytokine and receptor subunits, and on the IL-27-induced signalling and downstream functions.
  • 批准号：
    197248
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $10.93万
  • 财政年份：
    2009
  • 负责人：
    Guzzo Christina R
  • 依托单位：
    Queen's University (Kingston, Ontario)