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The incorporation of human proteins into the external HIV envelope: using novel tools to phenotype viral surfaces and identify new antiviral targets.

The incorporation of human proteins into the external HIV envelope: using novel tools to phenotype viral surfaces and identify new antiviral targets.
将人类蛋白质纳入外部 HIV 包膜：使用新工具对病毒表面进行表型分析并识别新的抗病毒靶点。
批准号：
438155
负责人：
Guzzo Christina R
金额：
$7.29万
依托单位：
University of Toronto Scarborough (ON)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2020
资助国家：
加拿大
项目状态：
已结题
起止时间：
2020-10-01 至 2021-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=438155&lang=en
关键词：
Cd4+ T Cells Clinical And Lab-Adapted Hiv Isolates Flow Virometry Hiv Envelope Glycoprotein (Gp120) Human Immunodeficiency Virus 1 (Hiv-1) Integrin Alpha 4 Beta 7 Peripheral Blood Mononuclear Cells (Pbmc) Virion-Incorporated Proteins Virus Immunoc

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中文摘要
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英文摘要
Despite the extraordinary progress made over the past 40 years in our understanding of HIV disease and the development of increasingly effective therapies to control the pandemic, AIDS remains one of the greatest scientific and public health challenges of
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Using Unique Methods in Flow Virometry to Identify and Study Proteins on the HIV Surface.
Molecular mechanism of HIV blockade by a novel antiviral chemokine, XCL1.
The effect of HIV infection and anti-retroviral therapy on expression levels of the IL-27 cytokine and receptor subunits, and on the IL-27-induced signalling and downstream functions.
  • 批准号：
    197248
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $10.93万
  • 财政年份：
    2009
  • 负责人：
    Guzzo Christina R
  • 依托单位：
    Queen's University (Kingston, Ontario)