Investigating the non-canonical roles of DEPDC5 in brain development and diseases by in vivo functional genomics

通过体内功能基因组学研究 DEPDC5 在大脑发育和疾病中的非典型作用

• 批准号: 468260
• 负责人: Samarut Eric
• 金额: $ 69.38万
• 依托单位: Centre hospitalier de l'Universit de Montral (CHUM)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-09-01 至 2027-09-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=468260&lang=en
• 关键词: Epilepsy; Functional Genomics; Genetics; Zebrafish

About 1% of the Canadian population is affected by epilepsy. Although many mutations in genes involved in neuronal excitability have been identified as causative, other mutations in non-classical epilepsy genes have also been found. This is the case of mu

大约1%的加拿大人患有癫痫。虽然许多涉及神经元兴奋性的基因突变已被确定为致病基因，但在非经典癫痫基因中也发现了其他突变。