Cardiac Fluid Dynamics and the Immersed Boundary Method

9302545 Peskin该奖项将支持心脏的计算研究，浸入边界法的发展，以及涉及浸入边界法的生物群落软件的生产。该项目的第一个组成部分将是创建一个足够高效和现实的心脏计算机模型，作为心脏功能计算研究的实用科学工具。该项目的一个目标是产生用于生物实验的成像模式（如彩色多普勒流，核磁共振成像）的模拟，以便计算机实验的输出可以直接与实验数据进行比较。这种类型的输出使模拟数据和实际数据之间的直接比较成为可能。在某种程度上，两者一致，这为模型的有效性提供了支持。这种比较的另一个好处是：如果模型是有效的，那么模拟数据可以用来增强可视化技术。该项目的软件组件将与匹兹堡超级计算中心共同开发。该项目得到了计算数学、生理学和计算生物学项目的支持。＊＊＊

9302545 Peskin This award will support computational studies of the heart, the development of the immersed boundary method, and the production of software involving the immersed boundary method for the biological community. The first component of the project will be the creation of a computer model of the heart that is efficient enough and realistic enough to be a practical scientific tool for the computational investigation of cardiac function. One goal of the project is to produce simulations of imaging modalities (e.g. color-Doppler flow, MRI) that are used in biological experimentation so that the output from the computer experiment can be directly compared to experimental data. This type of output make possible a direct comparison between simulated and actual data. To the extent that the two agree, this lends support to the validity of the model. Another benefit from such comparison is this: if the model is valid \, then the simulated data can be used to enhance the visualization technique. The software component of this project will be develop in conjunction with the Pittsburgh Supercomputing Center. The project is being supported by the Computational Mathematics, the Physiology, and the Computational Biology programs. ***