Assessing functional impacts of disease-associated mutations in G-protein “other”
Assessing functional impacts of disease-associated mutations in G-protein “other”
批准号:
486559
负责人:
Alonzi Nicholas A
金额:
$1.27万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2022
资助国家:
加拿大
项目状态:
已结题
起止时间:
2022-12-01 至 2023-12-01
中文摘要
g蛋白是GTP酶,可水解GTP,在不同细胞间传递胞内信号,并在激活后维持体内平衡。g蛋白的调节因子分为促进g蛋白活化的鸟嘌呤核苷酸交换因子(GEFs)
英文摘要
G-proteins are GTPases that hydrolyze GTP, conduct intracellular signals across various cells, and maintain homeostasis upon activation. Regulators of G-proteins are divided into guanine nucleotide exchange factors (GEFs) which promote G-protein activatio
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