Phytochemical Endocrinology

植物化学内分泌学

• 批准号: 9304633
• 负责人: Patricia Whitten
• 金额: $ 5万
• 依托单位: Emory University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-07-15 至 1995-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9304633&HistoricalAwards=false
• 关键词: Phytochemical; Endocrinology

There are clear suggestions that elements of the diet influence the physiology of reproduction in primates, including humans. Some plant chemicals mimic the actions of animal steroids and therefore may directly influence reproductive function and even development. This project will develop a set of methods appropriate for investigating these actions in a natural setting. The investigator will develop three lines of analysis. First, she will directly assay phytochemical in plants foods eaten by humans and primates. Second, she will attempt to develop a steroid analysis reproductive function in natural populations via fecal steroid analysis, validating these results by comparing them with serum profiles. The third line of analysis will relate phytochemical intake to reproductive responses.

有明确的证据表明，饮食元素会影响灵长类动物（包括人类）的繁殖生理机能。 一些植物化学物质模仿动物类固醇的作用，因此可能直接影响生殖功能甚至发育。 该项目将开发一套适合在自然环境中调查这些行为的方法。 研究者将进行三线分析。 首先，她将直接测定人类和灵长类动物食用的植物食品中的植物化学物质。 其次，她将尝试通过粪便类固醇分析来开发自然群体中的类固醇分析生殖功能，并通过与血清谱进行比较来验证这些结果。 第三条分析将植物化学物质的摄入量与生殖反应联系起来。