Integrated Program in Endocrinology Translational Postdoctoral Training Program

内分泌学综合项目转化博士后培训项目

• 批准号: 10390410
• 负责人: IAN M. BIRD
• 金额: $ 32.91万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-05-01 至 2026-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10390410
• 关键词: Endocrinology; Training Programs; post-doctoral training; programs

Abstract. The rate of progress in understanding the basis for reproductive health and disease is breathtaking, accelerated ever further by constant advances in cellular and molecular techniques. Nonetheless, research in traditional academic departments and research in clinical departments often does not overlap. As such, the PhD trained in a purely academic environment will remain unexposed to the clinical mindset and practices and so fail to pursue translational goals, while the clinician Fellow is well aware of the clinical problem and by definition focused on the human itself, but may be less aware of recent conceptual and methodologic advances available to investigate clinically derived research questions. As PA-18-403 RFA states, “past studies have shown that health professional trainees who train in programs with postdoctoral researchers who have intensive research backgrounds are more likely to apply for and receive subsequent research grant support”. To that end, the goal of this proposal is simple - to provide for the PhD and MD Fellow a combined and integrated immersion experience in a cutting edge cross campus research program that is in itself embedded in and focused upon a more clinical environment where health and disease is the primary consideration, and to then promote the use of nonhuman primate and human derived models in MD or PhD Fellowship projects lead by MD/DVM/PhD Faculty of combined clinical and traditional training backgrounds. The campus home for this program will be the integrated Program in Endocrinology (iPEnd), which was founded in 2016 to foster and promote collaboration focused on fetal development and the compromised adult outcomes of adverse pregnancy. We propose here that iPEnd also offers a vibrant interdisciplinary and multidisciplinary environment comprised of MD, PhD and DVM trained faculty with which both MD and PhD Postdoctoral Fellows could train together to enter the world of translational research. Such a blended training environment is very much needed if we are to maintain a future pool of interdisciplinary translational research team members intellectually and professionally ready to pursue the goals of NICHD to improve reproductive health and outcomes. Another consideration by NIH is that trainees do not go on to future independent success by simple exposure to ‘good science’ alone. Indeed, both Trainees and Trainers need support and professional education to ensure the best outcomes. To that end, our proposed training includes a deep immersion in higher level research training typical of many T32 programs at this time, but we aim to go far beyond to include the evidence based 8 core competencies for Postdoctoral trainees combined with added Mentee and Mentor training and the complimentary Professional Development Resources in order to achieve the rich blended training environment so strongly recommended by NIH. We believe iPEnd is ready to promote the concepts of the interdisciplinary and multidisciplinary ‘Translational Workforce’ through the proposed Training Program, operating within first class campus environment geared for basic but increasingly supportive of translational research. On that basis, we submit this application.

抽象的。在了解生殖健康和疾病的基础方面取得了令人惊叹的进展， 细胞和分子技术的不断进步进一步加速了这一进程。尽管如此，在 传统的学术科室和临床科室的研究往往不重叠。因此，博士生 在纯粹的学术环境中接受培训将不会接触到临床思维和实践，因此会失败 在临床医生充分意识到临床问题和定义的情况下，追求翻译目标 专注于人类本身，但可能不太了解最近可用的概念和方法方面的进展 研究临床衍生的研究问题。正如PA-18-403RFA所述，“过去的研究表明 健康专业实习生，在项目中接受博士后研究人员的培训，博士后研究人员具有深入的研究 背景更有可能申请和获得随后的研究资助“。为此，目标是 这项建议很简单--为博士和医学博士提供一种结合和整合的沉浸 在前沿的跨校园研究项目中的经验，该项目本身嵌入并专注于 更多的临床环境中，健康和疾病是首要考虑的，然后才能推广使用 由MD/DVM/PHD领导的MD或PHD奖学金项目中的非人灵长类和人类衍生模型 具有临床和传统相结合的培训背景。该项目的校园所在地将是 内分泌学综合计划(IPEnd)，成立于2016年，旨在促进和促进合作 重点关注胎儿发育和不良妊娠损害的成人后果。我们在这里求婚 IPEnd还提供了一个充满活力的跨学科和多学科环境，由医学博士、博士和 DVM培训的教员，医学博士和博士后研究员可以一起培训进入世界 翻译研究。如果我们想要保持未来，这样的混合训练环境是非常必要的 跨学科的翻译研究团队成员，在智力和专业上都准备好了 NICHD改善生殖健康和结果的目标。NIH的另一个考虑是实习生 不要仅仅通过简单地接触“好的科学”来获得未来的独立成功。事实上，两位实习生 培训人员需要支持和专业教育，以确保取得最佳结果。为此，我们提出的 培训包括深度沉浸在更高水平的研究培训中，这是目前许多T32项目的典型， 但我们的目标远远不止于包括基于证据的8项核心能力，供博士后实习生使用 与增加的学员和导师培训以及免费的专业发展资源相结合 为了达到NIH极力推荐的丰富的混合式培训环境。我们相信iPEnd 准备通过以下方式促进跨学科和多学科的“翻译劳动力”的概念 拟议的培训方案，在一流的校园环境中运行，面向基本但 越来越多地支持翻译研究。在此基础上，我们提交了这份申请。