Do a5GABAA Receptors Mediate the Antidepressant Properties of Nitrous Oxide?

a5GABAA 受体是否介导一氧化二氮的抗抑郁特性？

• 批准号: 486599
• 负责人: Brenna Connor
• 金额: $ 1.27万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-12-01 至 2023-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=486599&lang=en
• 关键词: Behaviour; Cellular Neurobiology; Depression; Electrophysiology; Gabaa Receptors; Mice; Molecular Neurobiology; Nitrous Oxide; Tonic Inhibition

About 12% of the population will suffer from depression in their lifetime, with significant negative impact on individuals, families, and society. However, current therapies can take weeks to work and are ineffective for many patients, which has led scien

大约12%的人口会在一生中遭受抑郁症的困扰，对个人、家庭和社会都会产生重大的负面影响。然而，目前的治疗方法可能需要几周的时间才能奏效，而且对许多患者无效，这导致了科学