Conference: Workshop on Steroid Hormones and Brain Function; Breckenridge, CO; April 4-8, 1993

为什么两性不同？ 简单的答案是类固醇 荷尔蒙 类固醇激素刺激细胞生长， 分化，也引发了性别典型的表达， 行为。 他们最重要的目标之一是大脑。 直到最近，人们还认为类固醇发挥了 通过与受体结合直接影响基因表达， 细胞核。 最近已经清楚，类固醇的作用 通过非基因组机制。 这些最新发现可能 需要一个“范式转变”的方式研究， 繁殖的进行，因为它似乎是， 类固醇作用比以前认为的要复杂得多。 在大型科学会议上， 学科之间往往相互影响， 必然会暴露在快速突破的发展中， 虽然与他们的工作有关，但涉及不熟悉的方法， 专业知识 这次会议的目的是把分子 研究人员与行为神经科学家一起， 合作，可以利用我们的最新进展， 了解类固醇激素的作用机制。

Why are the two sexes different? The simple answer is steroid hormones. Steroid hormones stimulate cell growth, sexual differentiation, and also trigger the expression of sex-typical behaviors. One of their most important targets is the brain. Until recently, it was thought that steroids exerted their effects directly on gene expression by binding to receptors in the cell nucleus. It has recently become clear that steroids act through nongenomic mechanisms as well. These recent findings may necessitate a "paradigm shift" in the way research into reproduction is conducted because it seems that the mechanisms of steroid action are much more complicated than previously thought. At large scientific meetings, practitioners of various disciplines tend to interact with each other and do not necessarily become exposed to fast breaking developments that, although relevant to their work, involve unfamiliar methods and expertise. The purpose of this conference is to bring molecular investigators together with behavioral neuroscientists to promote collaborations that can capitalize on recent advances in our understanding of the mechanism of steroid hormone action.