Cyclic Phosphorus and Anionic Silicon Compounds

9312053马萨诸塞州霍姆斯大学-阿默斯特分校Holmes，马萨诸塞州大学化学系，得到无机、生物无机和有机金属化学项目的支持，与喀山州立大学的Rauza P. Arshinova博士合作开展美俄合作科学项目。，俄罗斯，以确定决定环状四配位和五配位硅以及五配位和六配位磷化合物的特性。俄罗斯小组将制备新的三配位和四配位环状磷和硅化合物。这些化合物将被俄罗斯和美国的研究小组用作合成五配位环状衍生物的前体。这些配合物将通过NMR光谱和X-射线衍射来研究，以确定环构象变化和配体交换现象。理论计算将被用来模拟这些过程，并了解磷和硅的亲核置换反应的能量学。 磷和硅的许多反应涉及一些试剂攻击磷或硅化合物以产生包含所有反应物质的中间体。该项目将联合收割机结合美国和俄罗斯的专业知识，以确定这些中间体的行为和什么反应途径是开放的。这项工作将特别集中在生物化学能量转移过程中重要的反应上。

9312053 Holmes University of Massachusetts - Amherst Dr. Robert R. Holmes, Chemistry Department, University of Massachusetts, is supported by the Inorganic, Bioinorganic, and Organometallic Chemistry Program for a US-Russia Cooperative Science Program with Dr. Rauza P. Arshinova, Kazan State Univ., Russia, to determine features which determine the properties of cyclic four- and five-coordinate silicon and five- and six-coordinate phosphorus compounds. New tri- and tetra-coordinate cyclic phosphorus and silicon compounds will be prepared by the Russian group. These will be used as precursors for five-coordinated cyclic derivatives to be synthesized by the Russian and US groups. These complexes will by studied by NMR spectroscopy and x-ray diffraction to determine ring conformational changes and ligand exchange phenomena. Theoretical calculations will be employed to model these processes and to understand the energetics of nucleophilic displacement reactions at phosphorus and silicon. Many reactions of phosphorus and silicon involve some reagent attacking a phosphorus or silicon compound to produce an intermediate containing all of the reacting species. This project will combine the expertise of a US and a Russian group to determine how these intermediates behave and what reaction pathways are open to them. The work will center particularly on reactions which are important in biochemical energy transfer processes.