U.S.-Japan Cooperative Research: Mechanisms Regulating Species Specific Ovulation Rates (Hamster, Guinea Pig)

美日合作研究：调节物种特定排卵率的机制（仓鼠、豚鼠）

• 批准号: 9319254
• 负责人: Gilbert Greenwald
• 金额: $ 1.05万
• 依托单位: University of Kansas Medical Center
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-04-01 至 1997-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9319254&HistoricalAwards=false
• 关键词: U.S.; Japan; Cooperative; Research; Mechanisms

9319254 Greenwald This award supports a two-year cooperative research project between Professor Gilbert Greenwald, Department of Physiology, University of Kansas Medical Center, Kansas City, Kansas, and Professor Kazuyoshi Taya, Laboratory of Veterinary Physiology, Tokyo Univesity of Agriculture and Technology, Tokyo. The joint project focuses on mechanisms regulating species-specific ovulation rates in mammals. The investigators will investigate the factors responsible for one species ovulating 1-3 ova (guinea pig) and another ovulating 10-12 ova (hamster). They will analyze the hypothalamic- pituitary-ovarian axis, with the Japanese group focusing on in vivo approaches and the U.S. investigator emphasizing in vitro methods. The question being addressed is timely and important to students of reproductive physiology and will enhance our understanding of the mechamisms underlying the determination of the numbers and extent of folliculat development during each follicular cycle. ***

小行星9319254 该奖项支持堪萨斯州堪萨斯城堪萨斯大学医学中心生理学系吉尔伯特格林沃尔德教授和东京农工大学兽医生理学实验室多谷和义教授之间为期两年的合作研究项目。 该联合项目的重点是调节哺乳动物物种特异性排卵率的机制。 研究者将研究导致一个物种排卵1-3个卵子（豚鼠）和另一个物种排卵10-12个卵子（仓鼠）的因素。 他们将分析下丘脑-垂体-卵巢轴，日本研究小组侧重于体内方法，美国研究人员侧重于体外方法。 正在解决的问题是及时和重要的生殖生理学的学生，并将提高我们的mechanamisms的基础上确定的数量和程度folliculat发展在每个卵泡周期的理解。 ***