Electric Field Interactions with Neural Tissue

这项名为《电场与神经元组织的相互作用》的研究项目的目的是研究电场控制和修饰神经元活动的机制。通过在特定位置放置电极并注入已知量的电流，可以很容易地在大脑神经元附近和周围产生电场。先前的实验表明，以非常小的幅度施加的电流能够阻止神经元的活动，并干扰它们的放电模式。这项研究的目的是确定这些影响的基本机制。研究提案的结果将让我们更好地了解电场如何控制神经元的活动，并可能导致设计一种方法来防止癫痫发作等异常神经元活动。

The goal of this research project entitled "Electric Field Interaction With Neuronal Tissue" is to study the mechanisms by which electric fields can control and modify the activity of neurons. Electric fields can be easily generated near and around neurons in the brain by placing electrodes in specific locations and injecting known amounts of current. Previous experiments have shown that currents applied at very small amplitudes are capable of preventing the activity of neurons and to interfere with their firing patterns. The research is aimed at the determination of the basic mechanisms underlying these effects. The results of the research proposal will allow us to better understand how electric fields can control the activity of neurons and may lead to the design of a method to prevent abnormal neuronal activity such as in epileptic seizures.