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I/UCRC for Collaborative Study of Surfaces and Biological Interactions

I/UCRC 表面和生物相互作用合作研究

基本信息

批准号：
9320054
负责人：
Anne Hiltner
金额：
$ 6万
依托单位：
Case Western Reserve University
依托单位国家：
美国
项目类别：
Continuing Grant
财政年份：
1993
资助国家：
美国
起止时间：
1993-09-15 至 1995-08-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=9320054&HistoricalAwards=false
关键词：
UCRC Collaborative Study Surfaces Biological

项目摘要

9320054 Hiltner This "TIE" project funds a research project to be performed jointly by Case Western Reserve University's Industry/University Cooperative Research Center for Applied Polymers Research and the State University of New York - Buffalo's Industry/University Cooperative Research Center for Biosurfaces. This project is a collaborative study of surface interactions that will lead to an elucidation of relationships between biomaterial surface properties and blood protein and monocyte/macrophage adhesion and activation. The Industry/University Cooperative Research Center for Applied Polymers will be responsible for the biological characterization both before and following protein adsorption. The Industry/University Cooperative Research Center for Biosurfaces will be responsible for surface characterization both before and following protein adsorption and cell adhesion. The researchers are very well qualified to perform this joint project. Additional funding is provided by the U.S. Department of Energy's Environmental Restoration and Waste Management Office to obtain a non-voting membership in the Industry/University Cooperative Research Center for Applied Polymers Research. The Program Manager recommends Case Western Reserve University be awarded $25,000 for the first year of a two-year continuing award. An additional $10,000 is recommended for one year with funding provided by the U.S. Department of Energy.

9320054 Hiltner这个“TIE”项目资助了一项研究项目，该项目将由凯斯西储大学应用聚合物工业/大学合作研究中心和纽约州立大学布法罗生物表面工业/大学合作研究中心联合进行。该项目是一项表面相互作用的合作研究，将导致阐明生物材料表面特性与血液蛋白和单核细胞/巨噬细胞粘附和激活之间的关系。工业/大学应用聚合物合作研究中心将负责蛋白质吸附前后的生物特性。工业/大学生物表面合作研究中心将负责蛋白质吸附和细胞粘附之前和之后的表面表征。研究人员完全有资格执行这个联合项目。美国能源部的环境恢复和废物管理办公室提供了额外的资金，以获得工业/大学应用聚合物研究合作研究中心的无投票权会员资格。项目经理建议凯斯西储大学在两年持续奖励的第一年获得25,000美元的奖励。建议在美国能源部提供的资助下，再提供1万美元，为期一年。