Stoichiometric and Catalytic Organic Transformations Using Early Transition Metal Aryloxide Compounds

9321906普渡大学罗思韦尔大学化学系Ian P.Rothwell博士在无机化学、生物无机化学和金属有机化学计划的支持下，对早期d-嵌段芳氧化合物和相关络合物用于进行化学计量和催化有机转化进行了合成和机械研究。芳氧钛化合物将用于催化(2+2+2)环加成合成1，3-环己二烯以及1，3-二烯与烯烃的选择性交叉偶联反应。将表征一种知之甚少的催化剂，用于将炔烃选择性三聚为富烯。合成了一种新的手性芳氧基化合物，并考察了其在不对称合成中的应用。我们将探讨所有这些反应的机理。催化剂是加速或促进化学反应的物种，在理论化学和应用化学的所有领域都很重要。在这项研究中，将为几个重要的过程开发新的、更有效的催化剂。将详细研究这些新催化剂的作用细节，以了解它们的行为，并允许获得更有效的催化剂。

9321906 Rothwell Purdue University Dr. Ian P. Rothwell, Chemistry Department, Purdue University, is supported by the Inorganic, Bioinorganic, and Organometallic Chemistry Program to carry out synthetic and mechanistic studies into the use of early d-block aryloxide and related complexes for carrying out stoichiometric and catalytic organic transformations. Titanium aryloxides will be used for the catalytic synthesis of 1,3-cyclohexadienes by (2+2+2) cycloaddition and for selective cross coupling of 1,3-dienes with olefins. A poorly understood catalyst for the selective trimerization of alkynes to fulvenes will be characterized. A new chiral aryloxide will be prepared and its use in asymmetric synthesis will be examined. Mechanisms for all of these reactions will be probed. Catalysts, species which speed or facilitate a chemical reaction, are important in all areas of pure and applied chemistry. In this study new, more effective catalysts will be developed for several important processes. The details of how these new catalysts act will be examined in detail in order to understand their behavior and to allow even more efficient catalysts to be obtained.