I-Corps: Catalytic Porous Organic Polymers

I-Corps：催化多孔有机聚合物

• 批准号: 2324992
• 负责人: Timothy Swager
• 金额: $ 5万
• 依托单位: Massachusetts Institute of Technology
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-06-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2324992&HistoricalAwards=false
• 关键词: Corps; Catalytic; Porous; Organic; Polymers

The broader impact/commercial potential of this I-Corps project is the development of catalytic materials that will enable the more efficient and green production of high value materials including pharmaceuticals and dyes. These proposed catalysts may be recycled or used for extended periods and are easily separated from the final products, which simplifies the manufacturing of these materials. In addition, the proposed materials materials have an advantage by making use of porous organic polymers that may provide solution-like reactivities as well as the advantages of a supported surface immobilized catalyst. The recyclable and ease of separation combine to create systems that may be used in conventional or emerging production methods and lower production costs. This I-Corps project is based on the development of new concepts in catalysis enabled by new generations of polymers with high degrees of internal free volume. These proposed polymers have high degrees of porosity and are created by molecular level designs that fuse non-compliant 3D monomers directly into the polymer backbone. The polymer structures are modular and can include structures capable of reactions that are promoted by light that oxidize of reduce compounds (photoredox reactivity), as well as thermochemical metal catalyzed reactions. Catalytic polymers can be bound to magnetic inorganic magnetic particles, glass sidewalls of reactors, on stirring turbines, or on the surfaces of tubing. The polymer structures and pockets around the catalytic sites can produce selectivity and high numbers of turnovers. In the case of photoredox catalytic materials, the polymers display much higher rates than molecular catalysts dissolved in solution, as a result of their excitonic and charge transporting abilities.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这个I-Corps项目的更广泛的影响/商业潜力是催化材料的开发，这将使包括药品和染料在内的高价值材料的更有效和绿色生产成为可能。这些提议的催化剂可以回收或延长使用时间，并且很容易从最终产品中分离出来，这简化了这些材料的制造。此外，所提出的材料材料具有利用多孔有机聚合物的优点，该聚合物可以提供类似溶液的反应性以及支撑表面固定化催化剂的优点。可回收性和易于分离性结合在一起，创造了可用于传统或新兴生产方法的系统，并降低了生产成本。这个I-Corps项目是基于新一代具有高度内部自由体积的聚合物在催化方面的新概念的发展。这些被提议的聚合物具有高度的孔隙度，并且是通过分子水平的设计，将不兼容的3D单体直接融合到聚合物骨架中。聚合物结构是模块化的，可以包括能够由光促进氧化或还原化合物（光氧化还原反应）的反应的结构，以及热化学金属催化反应。催化聚合物可以结合到磁性无机磁性颗粒，反应器的玻璃侧壁，搅拌涡轮机或管道表面上。在催化位点周围的聚合物结构和口袋可以产生选择性和高的周转率。在光氧化还原催化材料的情况下，聚合物表现出比溶解在溶液中的分子催化剂高得多的速率，这是由于它们的激子和电荷传输能力。该奖项反映了美国国家科学基金会的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。