Signaling in Plant Development and in Response to the Environment

植物发育和响应环境中的信号传导

• 批准号: 9354969
• 负责人: Daniel Cosgrove
• 金额: $ 67.5万
• 依托单位: Pennsylvania State Univ University Park
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-08-01 至 2004-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9354969&HistoricalAwards=false
• 关键词: Signaling; Plant; Development; Response; Environment

Signal transduction is emerging as an important principle underlying much of plant development and adaptation to the environment. Signaling often involves multiple levels of response, from organ, tissue and cell interactions to events at the level of membranes, cytoplasm and gene expression. In our view, the most informative analyses of signal transduction involve multidisciplinary approaches where the signal is characterized through its multiple levels and forms of expression (genetic, biochemical, physical, physiological, etc.) We propose to establish a graduate training program with innovations in our instructional approach and research guidance with faculty from six (6) departments to pursue collaborative research across multiple levels of signal transduction. Toward this goal, we will develop a problem-based learning course to explore multiple facets of plant signal transduction. Graduate students will engage in multidisciplinary research by attacking research problems at the interface of two (or more) research efforts. An annual Distinguished Investigator seminar/workshop series and concluding international symposium will provide additional opportunity for student development. Our program will enrich the background and "tool-kit" available to the next generation, as well as the current generation, of researchers to investigate the mechanisms by which plants develop and react to their environment.

信号转导是植物发育和适应环境的重要原理。信号通常涉及多个层面的反应，从器官、组织和细胞的相互作用到膜、细胞质和基因表达水平的事件。在我们看来，对信号转导最具信息量的分析涉及多学科方法，其中信号通过其多个层次和表达形式（遗传，生化，物理，生理等）进行表征。我们建议与来自六(6)个部门的教师建立一个研究生培训计划，在我们的教学方法和研究指导上进行创新，以追求信号转导的多个层次的合作研究。为了达到这个目标，我们将开发一个基于问题的学习课程来探索植物信号转导的多个方面。研究生将通过在两个（或更多）研究工作的界面上攻击研究问题来从事多学科研究。每年的杰出研究者研讨会/研讨会系列和最后的国际研讨会将为学生的发展提供额外的机会。我们的计划将丰富的背景和“工具箱”可用的下一代，以及当前的一代，研究人员的机制，植物的发展和对其环境的反应。