Cross-talk between host antiviral and apoptotic signaling pathways in de novo Dengue virus infection

新发登革热病毒感染中宿主抗病毒信号通路和细胞凋亡信号通路之间的串扰

• 批准号: 229060
• 负责人: Lin Rongtuan
• 金额: $ 16.39万
• 依托单位: CIUSSS de Centre-Ouest-de-l'Ile-de-Montral-Jewish General
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-03-01 至 2014-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=229060&lang=en
• 关键词: Apoptosis; Cytokine; Interferon; Irfs; Molecular Biology; Nf-Kb; Rig-I?Mda5; Signal Transduction; Transcription; Virus

Dengue viruses (DENVs) are globally important human pathogens infecting 50-100 million people annually, with ~25-50 thousand deaths, mainly affecting children. DENV is one of the most important public health problems in tropical and subtropical regions of

登革热病毒（denv）是全球重要的人类病原体，每年感染5000万至1亿人，造成2.5万至5万人死亡，主要影响儿童。DENV是热带和亚热带地区最重要的公共卫生问题之一