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Investigating the role of TRAF7 in regulating antiviral immune response

Investigating the role of TRAF7 in regulating antiviral immune response
研究 TRAF7 在调节抗病毒免疫反应中的作用
批准号：
414079
负责人：
Lin Rongtuan
金额：
$7.29万
依托单位：
Lady Davis Institute for Medical Research (Mtl)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2019
资助国家：
加拿大
项目状态：
已结题
起止时间：
2019-09-01 至 2020-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=414079&lang=en
关键词：
Hsv1 Immunofluorescence Influenza Virus Innate Immune Response S-Tag Purification Technique Tamoxifen-Inducible Ko Mice Tbk1 Traf7 Traf7flox/Flox Lys2-Cre Mice Ubiquitination

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英文摘要
Type I interferons is essential for host to fight against viral infection. However, the excessive IFN I production results in either tissue damage or autoimmune diseases under worse condition. To ensure successful antiviral defenses and to avoid aberrant
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