RUI: Rates and Mechanism of Grignard Reagent Formation by In situ Photomicrography of Magnesium Surfaces and Scanning Electrochemical Microscopy

RUI：通过镁表面原位显微摄影和扫描电化学显微镜观察格氏试剂形成的速率和机制

• 批准号: 9405038
• 负责人: Walter Bowyer
• 金额: $ 10.1万
• 依托单位: Hobart and William Smith Colleges
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-12-01 至 1998-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9405038&HistoricalAwards=false
• 关键词: RUI; Rates; Mechanism; Grignard; Reagent

Walter Bowyer and his undergraduate students at Hobart and William Smith Colleges will investigate the mechanism of Grignard reagent formation with the support of this forty-two month continuing grant from the Analytical and Surface Chemistry Program. The surface of the reacting magnesium metal will be characterized using photomicrography, scanning electrochemical microscopy, and kinetic studies. The goal of this research is to develop a fundamental, detailed understanding of the surface processes involved when alkyl halides react with metallic magnesium to form synthetically important Grignard reagents. Grignard reagents are among the most commonly utilized organic reagents, however, the factors controlling the production of these species are not well understood. In this research project, designed for undergraduate participation, Professor Bowyer and his students will characterize the mechanism of reagent formation occuring at the surface of magnesium metal. The results from these studies will permit much better control of the synthesis of these extraordinarily useful reagents that are employed broadly in commercial processes.

沃尔特·鲍耶和他在霍巴特和威廉·史密斯的本科生 学院将研究格利雅试剂的形成机制 在这42个月的持续资助下， 分析和表面化学程序。 反应的表面 镁金属将使用显微摄影，扫描， 电化学显微镜和动力学研究。 这个目标 研究是为了发展一个基本的，详细的了解， 当烷基卤化物与金属反应时涉及的表面过程 镁形成合成上重要的格氏试剂。 格氏试剂是最常用的有机试剂之一， 然而，控制这些物种产量的因素并不 很好理解。 在这个研究项目中， 参与，鲍耶教授和他的学生将描述 镁表面试剂生成机理 金属. 这些研究的结果将允许更好地控制 这些非常有用的试剂的合成 广泛应用于商业过程。