RPG: Toward a Genetic and Molecular Analysis of 18-Wheeler Function

RPG：对 18 轮功能进行遗传和分子分析

• 批准号: 9408269
• 负责人: Elizabeth Eldon
• 金额: $ 1.79万
• 依托单位: University of Notre Dame
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-09-01 至 1996-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9408269&HistoricalAwards=false
• 关键词: RPG; Toward; Genetic; Molecular; Analysis

9408269 Eldon ABSTRACT Once an egg cell divides, the two cells communicate with each other. If separated they would each divide to make a complete organism, but if they remain together, each contributes to half the organism. How and what embryonic cells signal to each other, then, is critical for normal development. Dr. Eldon is using embryonic development in the fruit fly, Drosophila melanogaster, to study a protein that may mediate communication between cells. From this study we hope to learn how signals between cells are transmitted and received.

【摘要】卵细胞一旦分裂，两个细胞就会相互沟通。如果它们分开，就会各自分裂成一个完整的有机体，但如果它们保持在一起，就各占有机体的一半。那么，胚胎细胞如何以及以何种方式相互传递信号，对正常发育至关重要。埃尔登博士正在利用果蝇（Drosophila melanogaster）的胚胎发育来研究一种可能介导细胞间交流的蛋白质。通过这项研究，我们希望了解细胞之间的信号是如何传递和接收的。