Biopsychology of Female Sexual Behavior

女性性行为的生物心理学

• 批准号: 9412605
• 负责人: Emilie Rissman
• 金额: $ 29.42万
• 依托单位: University of Virginia Main Campus
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-09-01 至 1998-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9412605&HistoricalAwards=false
• 关键词: Biopsychology; Female; Sexual; Behavior

The goal of this research is to study the regulation by the nervous system of the female sexual behavior of an animal that displays sexual receptivity at all times of the cycle and year, the female musk shrew. Musk shrews are primitive mammals from tropical and subtropical areas of Southeastern Asia. Reproduction is not cyclic, but occurs year round whenever local conditions are favorable. Female musk shrews maintain high levels of serum testosterone. Experiments are designed to test the idea that conversion of testosterone to estrogen in certain parts of the brain are critical for the activation of female sexual behavior. In musk shrews mating occurs when estrogen levels are low and testosterone concentrations are high. The conversion of testosterone to estrogen to activate sexual behavior is better than maintaining high levels of estrogen since estrogen can act as a neurotoxin. Androgens have been implicated in the expression of female sexual behavior in other animals so these studies may shed light on neural regulation of female sexual behavior in other female animals.

这项研究的目的是研究神经系统对雌性麝香鼩性行为的调节，这种动物在周期和年份的所有时间都表现出性接受能力。麝鼠是东南亚热带和亚热带地区的原始哺乳动物。繁殖不是周期性的，而是一年四季，只要当地条件有利。雌性麝鼩保持高水平的血清睾酮。 实验的目的是测试这样一种观点，即大脑某些部位的睾酮转化为雌激素对激活女性性行为至关重要。 在麝香鼩交配发生时，雌激素水平低，睾丸激素 浓度很高。 的 转换 从睾丸激素到雌激素来激活性行为比维持高水平的雌激素更好，因为雌激素可以作为神经毒素。雄激素与其他动物雌性性行为的表达有关，因此这些研究可能有助于阐明其他雌性动物雌性性行为的神经调节。