Renovation of Research Facilities in the Department of Biochemistry

生物化学系研究设施改造

• 批准号: 9415022
• 负责人: Roger McMacken
• 金额: $ 89.62万
• 依托单位: Johns Hopkins University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-04-01 至 1998-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9415022&HistoricalAwards=false
• 关键词: Renovation; Research; Facilities; Department; Biochemistry

The NSF award to John Hopkins University will be utilized to redesign and completely renovate facilities for the Biochemistry Department in the School of Hygiene and Public Health, east Baltimore, MD. The School, the first public health school in the Unites States, offers multiple programs in the basic biological and environmental sciences and provides leadership in biochemical and biotechnological research and education. The Biochemistry department is oriented towards studies of fundamental biological problems which are carried out at the interface of biology and chemistry. Fundamental chemical, biochemical, molecular biological, structure, biophysical and genetic approaches are stressed in order to understand the mechanisms of biological processes in experimentally-accessible systems. NSF support will be matched with institutional funds to redesign and renovate decaying laboratories on three floors of the Hygiene building, the core of which was constructed in 1926. Building additions were constructed in 1963 and 1968. The original building was last renovated approximately 40 years ago; the additions have not been renovated since construction. The three-year renovation project will correct research space which is poorly configured in very small laboratories, inhibiting spontaneous interactions, communication and intellectual exchange among researchers. Centralized instrumentation rooms facilities will be constructed. Ten additional chemical fume hoods, a cold room, and vented solvent cabinets will be installed, as will new casework, including benchtops which are resistant to concentrated acids and bases, organic solvents, and radioactive fluids. The renovations will have immediate impact on the ten current faculty and will be a major resource in attracting two new faculty. The new laboratories will facilitate more training opportunities for graduate students, as bench space will be greatly increased through the redesign effort. Over the next f ive years, the department will have 65 graduate students, 50 postdoctoral fellows and 15 undergraduates who will be part of a critical mass of researchers working in the area of enzyme mechanisms and protein structure and function -- areas critical to leadership in the next stage of biotechnology.

美国国家科学基金会授予约翰霍普金斯大学将用于重新设计和完全翻新设施的生物化学系在卫生和公共卫生学院，东巴尔的摩，马里兰州。 学校是美国第一所公共卫生学校，提供基础生物和环境科学的多个课程，并在生物化学和生物技术研究和教育方面发挥领导作用。生物化学系面向在生物学和化学的界面上进行的基本生物学问题的研究。 强调基本化学，生物化学，分子生物学，结构，生物物理和遗传方法，以了解实验可访问系统中的生物过程的机制。 NSF的支持将与机构资金相匹配，以重新设计和翻新卫生大楼三层楼的腐烂实验室，其核心建于1926年。 1963年和1968年建造了建筑物。 原来的建筑最后一次翻修是在大约40年前;增建部分自建造以来没有翻修过。 为期三年的改造项目将纠正在非常小的实验室中配置不良的研究空间，抑制研究人员之间的自发互动，沟通和智力交流。 将建造集中仪表室设施。 将安装另外十个化学通风柜、一个冷藏室和通风溶剂柜，以及新的个案工作，包括耐浓酸和碱、有机溶剂和放射性液体的工作台。 翻修将对现有的十名教师产生直接影响，并将成为吸引两名新教师的主要资源。 新的实验室将为研究生提供更多的培训机会，因为通过重新设计工作将大大增加工作台空间。 在未来五年内，该系将有65名研究生，50名博士后研究员和15名本科生，他们将成为从事酶机制和蛋白质结构与功能领域研究的关键人员的一部分-这些领域对生物技术下一阶段的领导至关重要。