International Conference on Ribosomes in Victoria, British Columbia, Canada May 20-25, 1995.
International Conference on Ribosomes in Victoria, British Columbia, Canada May 20-25, 1995.
批准号:
9417985
负责人:
Walter Hill
金额:
$0.5万
依托单位:
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
1995
资助国家:
美国
项目状态:
已结题
起止时间:
1995-04-01 至 1996-03-31
中文摘要
在过去的二十年里,大约每三年就举行一次关于核糖体的国际会议。这些会议的目的是回顾目前对核糖体的结构/功能以及这种复杂大分子与蛋白质生物合成所需的其他因子和配体的相互作用的研究。私人 将讨论的主题包括rRNA结构/功能; rRNA合成,加工和组织;核糖体蛋白质结构/功能; rRNA/r蛋白质相互作用;核糖体组装;翻译装置的进化; mRNA相互作用,tRNA相互作用;翻译的保真度;和外在因素/抗生素与核糖体的相互作用。这次会议将于1995年5月20日至25日在不列颠哥伦比亚省的维多利亚举行,它将对核糖体研究的国际努力产生重大影响。 这是一个世界各地从事该领域工作的工作者相互交流的时间,讨论自上次会议(柏林,1992年)以来取得的进展,并概述预计今后将开展的工作。总结核糖体及其在蛋白质生物合成中的作用的优秀书籍来自大多数以前的会议。 这本书也是为这次会议准备的。 这些书籍成为相当标准的研究实验室在世界各地的综合参考所做的工作在这个复杂的领域。 %%% 核糖体是蛋白质合成的细胞机器。核糖体领域是一个小而充满活力的研究竞技场,为世界各地的许多工作者。 尽管这一领域并不像以前那样受欢迎,但许多重要的研究和许多进展都有规律地发生。 对核糖体的进一步研究对我们理解蛋白质合成至关重要。 在过去几年里,特别令人感兴趣的是越来越多的证据表明,核糖体以一种柔韧的方式与tRNA(结构RNA)和mRNA(携带编码蛋白质的信息)相互作用。 这次会议的一个主要重点是理解量化宽松复杂相互作用的动力学。这次会议定于1995年5月20日至25日在不列颠哥伦比亚省的维多利亚举行,它将对国际上在核糖体研究方面所作的努力产生重大影响。
英文摘要
Approximately every three years, for the past twenty years, international meetings have been held on the subject of ribosomes. The purpose of these meetings is to review the current research on the structure/function of the ribosome and the interactions of this complex macromolecule with other factors and ligands necessary for protein biosynthesis. PRIVATE Topics to be discussed include rRNA structure/function; rRNA synthesis, processing and organization; ribosomal protein structure/function; rRNA/r protein interactions; ribosome assembly; evolution of the translational apparatus; mRNA interactions, tRNA interactions; fidelity of translation; and extrinsic factors/antibiotic interactions with ribosomes. This meeting, scheduled to be held May 20 25, 1995 in Victoria, British Columbia, will have a major impact on the international efforts being made in ribosome research. It is a time when workers in the field from around the world will interact, discussing the progress made since the last meeting (Berlin, 1992) and outline that work which is expected to transpire in the future. Excel lent books summarizing the ribosome and its role in protein biosynthesis have emanated from most of the previous conferences. Such a book is planned for this conference as well. These books become rather standard in research laboratories throughout the world as comprehensive references for the work done in this complex field. %%% The ribosome is the cellular machinery for protein synthesis. The ribosome field is a small but vibrant research arena for many workers throughout the world. Even though this field does not enjoy all of the popularity it once did, much critical research and many advances take place with great regularity. Further research on ribosomes is essential to our understanding of protein synthesis. Of special interest in the last few years is the evidence mounting that the ribosome interacts in a pliable way with tRNA (the structural RNA) and mRNA (which carries the message to encode the protein). A main emphasis of this meeting is to understand the dynamics of theqe complex interactions. This meeting, scheduled to be held May 20-25, 1995 in Victoria, British Columbia, will have a major impact on the international efforts being made in ribosome research.
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海外基金