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Cellular and molecular mechanisms of Natural Killer cell-mediated vascular remodeling in pulmonary arterial hypertension

Cellular and molecular mechanisms of Natural Killer cell-mediated vascular remodeling in pulmonary arterial hypertension
自然杀伤细胞介导的肺动脉高压血管重塑的细胞和分子机制
批准号：
355730
负责人：
Ormiston Mark L
金额：
$60.47万
依托单位：
Queen's University (Kingston, Ontario)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2016
资助国家：
加拿大
项目状态：
已结题
起止时间：
2016-10-01 至 2021-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=355730&lang=en
关键词：
Angiogenesis Cardiopulmonary Phenotyping In Mice Cardiovascular Immunology Natural Killer Cells Pulmonary Arterial Hypertension

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英文摘要
Pulmonary arterial hypertension (PAH) is a fatal disease that preferentially targets young women in their 30s and 40s. PAH involves a loss of blood vessels in the lung. This loss leads to increased stress on the right side of the heart and eventual death
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Cellular and molecular mechanisms of Natural Killer cell-mediated vascular remodeling in pulmonary arterial hypertension