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Control of hematopoietic cell fate by LMO2

Control of hematopoietic cell fate by LMO2
LMO2 对造血细胞命运的控制
批准号:
366612
负责人:
Hoang Trang K
金额:
$7.29万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-11-01 至 2017-11-01

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中文摘要
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英文摘要
Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Our efforts are aimed at understanding how the LMO2 oncogene induce T-ALL. This oncogene is activated in childhood T-ALL by different mechanisms, one of which was widely discussed in
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会议论文
Uncovering tumor specific antigens and vulnerabilities in ETP-acute lymphoblastic leukemia
Modelling T cell leukemogenesis in mice
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