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Uncovering tumor specific antigens and vulnerabilities in ETP-acute lymphoblastic leukemia

Uncovering tumor specific antigens and vulnerabilities in ETP-acute lymphoblastic leukemia
揭示 ETP-急性淋巴细胞白血病的肿瘤特异性抗原和脆弱性
批准号:
480030
负责人:
Hoang Trang K
金额:
$62.42万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
未结题
起止时间:
2023-03-01 至 2028-03-01

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中文摘要
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英文摘要
Standard of care in pediatric T-cell acute lymphoblastic leukemia (T-ALL) includes topoisomerase inhibitors, microtubule targeting drugs and corticosteroids that are administered over a two-year treatment regimen. Despite cure rates of 90%, the long durat
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