Chemical and Physical Properties of 2-Aminopyrroles

2-氨基吡咯的化学和物理性质

• 批准号: 9420655
• 负责人: Michael De Rosa
• 金额: $ 14.71万
• 依托单位: Pennsylvania State Univ University Park
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-05-01 至 1998-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9420655&HistoricalAwards=false
• 关键词: Chemical; Physical; Properties; Aminopyrroles

With funding from the Organic Dynamics Program, Professor DeRosa of Penn. State-Delaware County Campus will characterize seminal compounds in the 2-aminopyrrole class of compounds. This will include both chemical and physical characterization as well as reaction profiles. From this work, it is anticipated that the electronic effect of the 2-amino substituent will be clearly established. Further, tautomeric isomers and roles of hydrogen exchange will be determined. Pyrrole is a fundamental building block in biological systems and its chemical reactions are quite significant. This project will elaborate the effects that substituents have on the chemistry of this important class of compounds. This research is also designed to have a major impact on undergraduate students which reflects on the future scientific enterprise.

在有机动力学项目的资助下，宾夕法尼亚大学的德罗莎教授。州立特拉华县校园将表征种子化合物在2-氨基吡咯类化合物。这将包括化学和物理表征以及反应概况。从这项工作中，预计2-氨基取代基的电子效应将被清楚地确定。此外，将确定互变异构体和氢交换的作用。吡咯是生物系统的基本组成部分，它的化学反应非常重要。这个项目将详细阐述取代基对这类重要化合物的化学作用。本研究也旨在对本科生产生重大影响，反映未来的科学事业。