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Comprehensive mapping and evolutionary dynamics of the mutational landscape of antimicrobial resistance

Comprehensive mapping and evolutionary dynamics of the mutational landscape of antimicrobial resistance
抗菌素耐药性突变景观的综合绘图和进化动力学
批准号：
389612
负责人：
Serohijos Adrian
金额：
$47.93万
依托单位：
Universit de Montral
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2018
资助国家：
加拿大
项目状态：
已结题
起止时间：
2018-09-01 至 2023-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=389612&lang=en
关键词：
Antibiotic Resistance Antimicrobial Resistance Beta-Lactamase Deep Mutational Scan Dihdropteroate Synthase Dihydrofolate Reductase Droplet Microfluidics Fitness Landscape Population Dynamics Population Genetics

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英文摘要
We are surrounded by bacteria that could potentially cause harmful infections. However, we have been able to keep them at bay because of antibiotics. Indeed, advances in medicine, such as chemotherapy, surgery, and treatment of chronic diseases, crucially
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