NSF Young Investigator

9457236本项目中开展的研究将通过综合实验、理论和计算研究，为软骨组织工程知识库的发展做出贡献。主要研究者希望表征关节软骨生物物理特性的空间变化，并将宏观与分子成分联系起来。软骨修复和退变的生物物理机制将通过与结构和功能反应相关的生物物理扰动来描述。

9457236 Sah Investigations to be conducted in this project will contribute to the development of a knowledge base for cartilage tissue engineering through integrative experimental, theoretical, and computational studies. The principal investigator expects to characterize the spatial variation of the biophysical properties of articular cartilage and relate the macroscopic to the molecular constituents. The biophysical mechanisms of cartilage repair and degeneration are to be delineated by relating biophysical perturbations to structural and functional responses.