Career Award

职业生涯奖

• 批准号: 9501212
• 负责人: Francois Baneyx
• 金额: $ 24.46万
• 依托单位: University of Washington
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-06-15 至 2000-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9501212&HistoricalAwards=false
• 关键词: Career; Award

9501212 Baneyx This project is on research to evaluate methods to facilitate the production of aggregation-prone recombinant proteins in soluble form in E, coli. This project includes studies to determine: (1) the effect of global deregulation of the heat-shock response using two different mutations; (2) the role of the ibp gene products on aggregation and whether they serve as chaperones; and (3) any synergistic effects of the various mutations. In addition to this research activity, the investigator will enhance education by developing a new course in advanced biotechnology. Also, the investigator has recently developed a textbook for use in genetic engineering laboratory courses. ***

9501212 Baneyx该项目是关于评估促进在大肠杆菌中以可溶形式生产易于聚集的重组蛋白的方法的研究。 该项目包括研究确定：（1）使用两种不同突变的热休克反应的整体失调的影响;（2）ibp基因产物在聚集中的作用，以及它们是否作为分子伴侣;和（3）各种突变的任何协同效应。 除了这项研究活动外，研究人员还将通过开发先进生物技术的新课程来加强教育。 此外，研究人员最近还编写了一本用于遗传工程实验室课程的教科书。 ***