Methods for the Synthesis of Biologically and Theoretically Important Organic Compounds

生物学和理论上重要的有机化合物的合成方法

• 批准号: 9502507
• 负责人: James Leahy
• 金额: $ 21.12万
• 依托单位: University of California-Berkeley
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-04-15 至 1998-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9502507&HistoricalAwards=false
• 关键词: Methods; Synthesis; Biologically; Theoretically; Important

The focus of this research is the development of rhodium catalyzed reactions for the formation of carbocyclic rings, the application of the Baylis-Hillman reaction to asymmetric synthesis and the synthesis of a propellane structure containing a sigma-allyl cation. The focus of the educational plan involves the teaching of chemistry by using a modular approach and developing an undergraduate research seminar program. With this CAREER award, the Synthetic Organic Program is supporting the research and educational plan of Dr. James W. Leahy of the Department of Chemistry at the University of California, Berkeley. Professor Leahy will focus his research efforts on the development of new methods for the catalytic formation of carbocyclic compounds and the preparation of a theoretically interesting fused- ring system containing a novel carbocation. The focus of Professor Leahy's educational plan involves the teaching of chemistry by using a modular approach and developing an undergraduate research seminar program.

本研究的重点是开发用于形成碳环的铑催化反应、Baylis-Hillman反应在不对称合成中的应用以及含有σ-烯丙基阳离子的丙烷结构的合成。教育计划的重点涉及使用模块化方法进行化学教学和开发本科生研究研讨会计划。 凭借这一职业奖，合成有机项目正在支持加州大学伯克利分校化学系 James W. Leahy 博士的研究和教育计划。 Leahy教授的研究重点是开发催化形成碳环化合物的新方法以及制备理论上有趣的含有新型碳阳离子的稠环系统。 Leahy 教授的教育计划的重点涉及使用模块化方法进行化学教学和开发本科生研究研讨会计划。