Ionic Organic Reactions and their Intermediates

离子有机反应及其中间体

• 批准号: 9504963
• 负责人: George Olah
• 金额: $ 42.3万
• 依托单位: University of Southern California
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-04-01 至 1998-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9504963&HistoricalAwards=false
• 关键词: Ionic; Organic; Reactions; their; Intermediates

The focus of this research includes three specific areas. First, the study of long-lived carbocations will be extended to the preparation of chiral carbocations for use as asymmetric catalysts for the Mukaiyama reaction. Second, Carbodications and polycations of theoretical, structural and synthetic interest will be studied by both experiment and theory. Third, gitonic protosolvation of alkyl cations, of carboxonium and acyl cations and dications, and of onium ions will be studied in superacidic systems. With this renewal award, the Synthetic Organic Program is supporting the research of Dr. George A. Olah, winner of the 1994 Nobel Prize in Chemistry, from the Department of Chemistry at the University of Southern California. Dr. Olah continues to focus his work on the study of organic ions and their reactions. Theoretical studies, the search for catalytic activity , and preparative reactions will be carried out

本研究的重点包括三个具体方面。首先，对长寿命碳正离子的研究将扩展到手性碳正离子的制备，以用作Mukaiyama反应的不对称催化剂。第二，理论上、结构上和合成上感兴趣的碳化和聚阳离子将从实验和理论两方面进行研究。第三，在超酸体系中研究烷基阳离子、羧基和酰基阳离子和阳离子以及洋葱离子的Gitonic原液溶解。通过这一更新的奖项，合成有机计划支持南加州大学化学系的乔治·A·奥拉博士的研究。奥拉博士是1994年诺贝尔化学奖获得者。奥拉博士继续致力于有机离子及其反应的研究。将进行理论研究、催化活性的探索和制备反应。