Ionic Organic Reactions and Their Intermediates

离子有机反应及其中间体

• 批准号: 9801722
• 负责人: George Olah
• 金额: $ 47.7万
• 依托单位: University of Southern California
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-04-15 至 2001-10-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9801722&HistoricalAwards=false
• 关键词: Ionic; Organic; Reactions; Their; Intermediates

Research involving the preparation, structural characterization, and reactivities of carboxonium, sulfonium and hydrido onium ions such as BH6+ and AlH6+ in superacid solutions will be continued. Structures and reactivities will be characterized by NMR spectroscopy, and where possible, isolable ionic salts will be crystallized and X-ray crystal structures determined. Theoretical calculations will be carried out in conjunction with the experimental work. New ways will be attempted to prepare simple but elusive carbocations - allyl, benzyl, cyclohexy, and phenyl - as well as more complex polycations such as 2,4,6-trisubstituted-1,3,5-tribenzyl (benzene) trications, and methanetetrakis(para-cumyl)tetrayl tetracation. With this renewal award, the Organic and Macromolecular Chemistry Program is continuing support for Drs. George A. Olah and Golam Rasul in the Department of Chemistry at the University of Southern California. Dr. Olah's Nobel Prize winning work on carbocations, or carbonium ions, was based on his observation that these unstable organic species, which had been proposed as reactive intermediates in organic reactions, could actually be observed spectroscopically by NMR and their structures and reactions studied in solution at low temperature, provided one had the right solvents and Lewis acids. These studies will provide a better understanding of electrophilic reactivity in strong acids, and are expected to lead to new synthetic methods in organic chemistry. The work will also provide valuable chemical research experience for postdoctoral and graduate students. ┤ ╣_║╝?└Á┤ ¢`¥©Á¥╣│ _Á¥©?┤¢ Â?╝ ¥©Á ║╝Á║/╝/¥╣? ? ?╝À/╣│ │?_║?┐┤¢ ¼©Á _Á¥©?┤??À` ▓/¢Á┤ ? ?╝À/?_Á¥/%%╣│ ╝Á/ÀÁ¥¢ ©/¢ ║?¥Á¥╣/% Â?╝ ┐¢Á ╣ ¥©Á ║╝Á║/╝/¥╣? ? ?╝À/╣│ │?_║?┐┤¢ ©/└╣À ╣¥Á╝Á¢¥╣À ▓╣?%?À╣│/% ║╝?║Á╝¥╣Á¢ ¿ ¥©╣¢ ┴?╝, ¢¥┐┤Á¥¢ ┴╣%% ╝Á│Á╣└Á ¥╝/╣╣À ┐¢ÁÂ┐% ╣ ┤Á└Á%

涉及制备、结构表征和 羧鎓、锍和异丙基鎓离子的反应性， BH 6+和AlH 6+在超强酸溶液中的研究将继续进行。 结构和 反应性将通过NMR光谱表征，并且其中 可能的话，可分离的离子盐将被结晶， 结构确定。 理论计算将在 结合实验工作。 将尝试新的方法， 制备简单但难以捉摸的碳阳离子-烯丙基，苄基，环己基，和 苯基-以及更复杂的聚阳离子， 2，4，6-三取代的-1，3，5-三苄基（苯）三环化合物，和 甲烷四（对枯基）四基四化。 有了这个更新奖，有机和高分子化学计划 继续支持乔治博士Olah和Golam Rasul在 南加州大学化学系。 博士 Olah获得诺贝尔奖的关于碳正离子的工作， 根据他的观察，这些不稳定的有机物种， 被提议作为有机反应中的活性中间体， 实际上可以通过NMR光谱观察到它们的结构， 在低温下研究溶液中的反应，条件是 合适的溶剂和刘易斯酸。 这些研究将提供更好的 了解强酸中的亲电反应性， 有望在有机化学中产生新的合成方法。 工作 还将为博士后提供宝贵的化学研究经验 和研究生。 什么？└Á┤ ¢`¥©Á¥╣│ - 什么？什么？你是说你是谁？?？╝À/╣│ │?_你说呢？┐┤¢ 你是谁？你？？` 你知道吗？?╝À/?_价格/% 你知道吗？¥/%？╝ ┐¢Á ╣ ¥©Á 你好，我是说你好吗？?？╝À/╣│ │?_你说呢？你知道吗？总氮/% 什么？║Á╝¥╣Á¢ 你说呢， 电子邮件