Polymer Solutions, Coil-Globule and Other Phase Transitions, US-Turkey Cooperative Research

产品描述：该项目支持马萨诸塞州大学高分子科学与工程教授Frank Karasz博士和两名土耳其科学家的合作：土耳其盖布泽马尔马拉研究中心（MRC）基础科学研究所所长Bahattin Baysal博士和土耳其科学家E. J. Elif Hamurcu是伊斯坦布尔Bogazici大学的研究助理，也是MRC聚合物研究项目的研究专家。 研究了稀溶液中高分子链从良溶剂中的膨胀线团到贫溶剂中的塌陷、致密的球状结构的转变。 通过实验或理论手段对链崩溃还没有一个全面和定量的了解。 这种现象与某些生物过程密切相关，包括DNA折叠和蛋白质变性以及三级结构形成。 在这个项目中，两位科学家将使用实验技术，包括动态光散射和粘度计，详细研究二元和三元体系中极性大分子在近θ条件下的线圈坍塌。 也将研究网络系统中的体积相变。 适用范围： 该项目汇集了两位在聚合物领域具有出色经验和强大研究能力的科学家。 Karasz博士用量热和散射方法研究了多肽的螺旋-卷曲转变，以及线性和星星、柔性和半柔性大分子在溶液中作为分子量、浓度、结构、离子强度和限制几何形状的函数的构象变化。 Baysal博士研究了稀溶液中的链特性，包括通过理论分析和粘度和介电实验进行的线圈到球的转变。这些互补的专业知识提供了他们的研究兴趣的逻辑组合。 MRC的一位博士后也将参与美国的这项研究。来自马萨诸塞州。 该项目符合国际方案司的目标。

Description: This project supports collaboration by Dr. Frank Karasz, Professor of Polymer Science and Engineering at the University of Massachusetts, and two Turkish scientists: Dr. Bahattin Baysal, Director, Research Institute of Basic Sciences at the Marmara Research Centre (MRC), Gebze, Turkey and Dr. E. Elif Hamurcu, a Reserach Assistant at Bogazici University in Istanbul and also a Research Specialist in the Polymer Research Project at the MRC. The research deals with the transition of a polymer chain in dilute solution from an expanded coil in a good solvent to a collapsed, compact globular structure in a poor solvent. A comprehensive and quantitative understanding of chain collapse has not yet been achieved through experimental or theoretical means. The phenomena is intimately related to certain biological processes, including DNA folding and protein denaturation and tertiary structure formation. In this project the two scientists will use experimental techniques, including dynamic light scattering and viscometry, in detailed studies of coil collapse in near theta conditions for polar macromolecules in binary and ternary systems. Volume-phase transitions in network systems will also be investigated. Scope: This project brings together two scientists with excellent experiences and strong capabilities in research in the field of polymers. Dr. Karasz has investigated the helix-coil transition of polypeptides with calorimetric and scattering methods, and the conformational variation of linear and star, flexible and semiflexible macromolecules in solution as functions of molecular weight, concentration, architecture, ionic strength and confining geometry. Dr. Baysal has studied chain characteristics in dilute solution including coil-to-globule transition with theoretical analysis and viscometric and dielectric experiments. These complementary expertise provide for a logical combination of their research interests. A postdoctorate from MRC also will participate in the research at the U. of Massachusetts. The project meets the objectives of the Division of International Programs.