Molecular Population Genetics of Drosophila
果蝇分子群体遗传学
基本信息
- 批准号:9509548
- 负责人:
- 金额:$ 30.5万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Continuing Grant
- 财政年份:1995
- 资助国家:美国
- 起止时间:1995-09-01 至 1999-08-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
9509548 LANGLEY The goal of this research is a quantitative understanding of the forces determining molecular genetic variation and divergence between species. Such understanding of the effects of mutation, recombination, natural selection and genetic drift is fundamental to effective applications in agricultural, conservation and medical genetics. The first project is a thorough and quantitative survey of DNA sequence variation at four genes near the tip of the X chromosome (where crossing over is much reduced) in four populations of Drosophila melanogaster. Several currently viable hypotheses attempt to explain the consistently observed reduction of heterozygosity in these regions of the genome. These models will be tested with the data from this survey. The second experiment is a parallel survey in D. simulans that will provide a "replication" and allow a careful analysis of the relationship between variation and divergence.
9509548兰利,这项研究的目标是定量地了解决定分子遗传变异和物种间差异的力量。这种对突变、重组、自然选择和遗传漂移的影响的理解是有效应用于农业、保护和医学遗传学的基础。第一个项目是对四个种群的果蝇X染色体顶端附近(交叉大大减少)的四个基因的DNA序列变异进行彻底和定量的调查。几个目前可行的假说试图解释在基因组的这些区域中持续观察到的杂合性降低。这些模型将用本次调查的数据进行检验。第二个实验是在拟D藻中进行的平行调查,它将提供“复制”,并允许仔细分析变异和分歧之间的关系。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Charles Langley其他文献
Neutralization–reionization of ions produced by electrospray
电喷雾产生的离子的中和-再电离
- DOI:
10.1016/s1387-3806(03)00217-3 - 发表时间:
2003 - 期刊:
- 影响因子:1.8
- 作者:
J. L. Seymour;E. Syrstad;Charles Langley;F. Tureček - 通讯作者:
F. Tureček
Charles Langley的其他文献
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{{ truncateString('Charles Langley', 18)}}的其他基金
Disertation Research: Adaptive Response to Transposable Element Invasion
论文研究:对转座元件入侵的适应性反应
- 批准号:
1010872 - 财政年份:2010
- 资助金额:
$ 30.5万 - 项目类别:
Standard Grant
Association Genetics of Natural Genetic Variation and Complex Traits in Pine
松树自然遗传变异与复杂性状的关联遗传学
- 批准号:
0501763 - 财政年份:2005
- 资助金额:
$ 30.5万 - 项目类别:
Continuing Grant
DISSERTATION RESEARCH: The Evolution of Disease Resistance in the genus Lycopersicon
论文研究:番茄属抗病性的演变
- 批准号:
9902342 - 财政年份:1999
- 资助金额:
$ 30.5万 - 项目类别:
Standard Grant
Dissertation Research: Mendel's First Law of Segregation Revisited: Variation in Chromosome Transmission Through Female Meiosis in Drosophila Melanogaster
论文研究:重新审视孟德尔第一分离定律:果蝇雌性减数分裂中染色体传递的变异
- 批准号:
9623970 - 财政年份:1996
- 资助金额:
$ 30.5万 - 项目类别:
Standard Grant
Drosophila Molecular Population Genetics
果蝇分子群体遗传学
- 批准号:
9117222 - 财政年份:1992
- 资助金额:
$ 30.5万 - 项目类别:
Continuing Grant
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濒危植物翅果油树Meta-population及其形成机理的研究
- 批准号:30470296
- 批准年份:2004
- 资助金额:8.0 万元
- 项目类别:面上项目
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