CAREER: Steroid-Mimicking Properties of Xenobiotics: Mechanisms of Action and their Role in Amphibian Declines

小行星9513362 这项研究的最终目标是评估和确定DDT等污染物和农药对全球两栖动物，特别是青蛙迅速消失的潜在作用。 这些污染物中的许多都像青蛙自身的物质一样作用于青蛙。 因此，对生理分子和机制的更深入理解最终可能不仅揭示基本的生存机制，而且揭示这些物种衰落的核心破坏性机制。 该项目的另一个重要推动力是让本科生和研究生参与项目的各个阶段，从而使他们不仅能够发展成为未来的科学家，而且还能够意识到生物生命的这种重大破坏。 ***

9513362 Hayes The ultimate goal of this study is to assess and define the potential role of pollutants and pesticides such as DDT on the rapid disappearance of amphibians worldwide, particularly frogs. Many of these pollutants act on the frogs as the animal's own substances do. Consequently, a deeper understanding of the physiologic molecules and mechanisms may ultimately shed light on not only basic survival mechanisms but also disruptive mechanisms which are at the core of the decline of these species. Another significant thrust of this project is to involve students, both undergraduate and graduate, in various stages of the project, thereby allowing them not only to develop as future scientists but also to acquire an awareness of this significant disruption of biological life. ***