A New Theoretical Model and Direct Experimental Verification of Thermal Equilibrium in Countercurrent Microvessels

逆流微容器热平衡的新理论模型及直接实验验证

• 批准号: 9523082
• 负责人: Sheldon Weinbaum
• 金额: $ 23.74万
• 依托单位: Research Foundation of the City University of New York
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-02-15 至 1999-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9523082&HistoricalAwards=false
• 关键词: New; Theoretical; Model; Direct; Experimental

ABSTRACT Lisa Xu 9523082 Heat transport between blood vessels and their surrounding tissues will be studied theoretically and experimentally. The focus of the work is on matched pairs of blood vessels between 80 and 200 microns in diameter, the model of which will be an exteriorized rat spinotrapezius muscle. The experimental approach includes infrared imaging of the tissue preparation and Doppler velocimetry of the blood flow. Exisitng analytical models will be evaluated and extended to support the experimental findings. Applications include tissue freezing, cryopreservation, laser surgery and hypothermia protocols.

摘要丽莎徐9523082 血管和周围组织之间的热传递将从理论和实验上进行研究。 这项工作的重点是直径在80到200微米之间的匹配血管对，其模型将是一个外置的大鼠脊髓肌肉。 实验方法包括组织制备的红外成像和血流的多普勒测速。 分析模型将被评估和扩展，以支持实验结果。 应用包括组织冷冻、低温保存、激光手术和低温方案。