STTR: Universal Detector for Molecular Identification in Separation Science

9523201 Schoen对分离科学分子检测和鉴定方法的研究，该方法将提供高灵敏度、选择性和与所有柱分离方法的相容性，将在本奖项下进行。将设计和构建一个带有色谱细胞的拉曼转导（SMART）检测器的原型超分子组件，用于气相色谱（GC）和高压液相色谱（HPLC）。该检测器将被设计为最佳灵敏度，并将适用于各类分析物。本研究结果将填补对通用、灵敏、选择性在线分子检测器的迫切需求。该产品还可以很容易地改造到已经安装的气相色谱，HPLC，毛细管电泳和超临界流体色谱仪器的基础上，增加了它在工业上的适用性。

9523201 Schoen Research into a method of molecular detection and identification for separation science that will provide high sensitivity, selectivity, and compatibility with all column separation methods will be conducted under this award. A prototype SupraMolecular Assembly for Raman Transduction (SMART) detector with a chromatographic cell will be designed and constructed to be used with Gas Chromatography (GC) and High Pressure Liquid chromatography (HPLC). This detector will be designed for optimal sensitivity and will be universal with respect to the class of analytes. The results of this research will fill the pressing need for a universal, sensitive, and selective on-line molecular detector. The product will also be easily retrofitted into the already installed base of GC, HPLC, Capillary Electrophoresis, and Supercritical Fluid Chromatography instruments, increasing its applicability in industry.