STTR: Universal Detector for Molecular Identification in Separation Science

9523201本奖项将为分离科学提供高灵敏度、高选择性和与所有柱分离方法兼容的分子检测和鉴定方法的肖恩研究。设计并构建了一种带有色谱池的拉曼转换(SMART)检测器的原型超分子组件，用于气相色谱(GC)和高压液相色谱(HPLC)。该检测器将为最佳灵敏度而设计，并且对于分析物类别而言将是通用的。这项研究的结果将满足对通用的、灵敏的和选择性的在线分子检测器的迫切需求。该产品还可以很容易地改装成现有的GC、HPLC、毛细管电泳仪和超临界流体色谱仪器，增加其在工业上的适用性。

9523201 Schoen Research into a method of molecular detection and identification for separation science that will provide high sensitivity, selectivity, and compatibility with all column separation methods will be conducted under this award. A prototype SupraMolecular Assembly for Raman Transduction (SMART) detector with a chromatographic cell will be designed and constructed to be used with Gas Chromatography (GC) and High Pressure Liquid chromatography (HPLC). This detector will be designed for optimal sensitivity and will be universal with respect to the class of analytes. The results of this research will fill the pressing need for a universal, sensitive, and selective on-line molecular detector. The product will also be easily retrofitted into the already installed base of GC, HPLC, Capillary Electrophoresis, and Supercritical Fluid Chromatography instruments, increasing its applicability in industry.