1996 Gordon Conference: Isotopes in Biology and Chemistry to be held in Ventura, California, February 11-16, 1996

1996年戈登会议：生物学和化学中的同位素将于1996年2月11日至16日在加利福尼亚州文图拉举行

• 批准号: 9527873
• 负责人: Judith Klinman
• 金额: $ 0.3万
• 依托单位: Gordon Research Conferences
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-02-15 至 1996-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9527873&HistoricalAwards=false
• 关键词: 1996; Gordon; Conference; Isotopes; Biology

9527873 Klinman Partial support is requested for the Gordon Research Conference on Isotopes in Biology and Chemistry to be held in Ventura, California, February 11-16, 1996. This long-standing conference has traditionally brought together investigators from a multitude of disciplines (e.g., physical and organic chemistry, atmospheric chemistry, and biological chemistry). As a result of its interdisciplinary nature, the Conference has served as a breeding ground for the generation of new concepts and methodologies in the biological sciences. Examples include the remarkable advances in enzymes kinetics that occurred in the 1980's: the recognition of the possible role of nuclear tunneling in enzyme reactions; the stimulation of a systematic study of the role of magnetic field effects in enzymatic reactions; the use of heavy atom isotope effects to probe plant physiology and evolution; etc. In recent years, the Conference has been moving increasingly into the area of biological chemistry. This trend is reflected in the current program which will range from a discussion of new aspects of H-transfer catalysis (low barrier hydrogen bonds, tunneling, and the role of proton pools in catalysis) to the use of isotopic probes to establish and characterize radical species in biological processes. A special session will be dedicated to a consideration of recent applications of heavy atom effects to characterize biological systems. Intermixed within this program will be sessions on both physical chemistry and reaction mechanisms. One particularly strong component of this conference is that it provides a format for the interaction of theoreticians with experimentalists. %%% Isotopes are widely used in biology and chemistry in order to follow processes and to understand function. This conference seeks to bring together scientists who use isotopes in an interdisciplinary manner in order to improve information exchange and allow exposure to new results. It is particularly important to the developm ent of biochemical tracer methodology that biologists be exposed to chemical applications of isotopes. ***

9527873克林曼部分支持请求戈登研究会议的同位素在生物学和化学将在文图拉，加州，1996年2月11日至16日举行。 这个历史悠久的会议传统上汇集了来自多个学科的研究人员（例如，物理和有机化学、大气化学和生物化学）。 由于其跨学科性质，会议已成为生物科学新概念和新方法产生的温床。 例如，20世纪80年代在酶动力学方面取得的显著进展：认识到核隧穿在酶反应中的可能作用;促进对磁场效应在酶反应中的作用进行系统研究;利用重原子同位素效应探测植物生理学和进化;近年来，会议越来越多地进入生物化学领域。 这一趋势反映在目前的计划，将从氢转移催化（低势垒氢键，隧道，和质子池在催化中的作用）的新方面的讨论，以使用同位素探针建立和表征生物过程中的自由基物种。 将举行一次特别会议，专门审议最近应用重原子效应确定生物系统特征的问题。 在这个计划中，将混合物理化学和反应机制的会议。 这次会议的一个特别重要的组成部分是，它为理论家与实验家的互动提供了一种形式。 同位素在生物学和化学中被广泛使用，以跟踪过程并了解功能。 本次会议旨在将以跨学科方式使用同位素的科学家聚集在一起，以改善信息交流并获得新成果。 生物学家接触同位素的化学应用对生物化学示踪方法学的发展尤为重要。 ***