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Glutamate excitotoxicity drives neurological death in leptomeningeal metastasis

Glutamate excitotoxicity drives neurological death in leptomeningeal metastasis
谷氨酸兴奋毒性导致软脑膜转移神经死亡
批准号:
471420
负责人:
Manoranjan Branavan
金额:
$10.2万
依托单位国家:
加拿大
项目类别:
Fellowship Programs
财政年份:
2022
资助国家:
加拿大
项目状态:
已结题
起止时间:
2022-09-01 至 2024-09-01

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中文摘要
翻译
软脑膜由覆盖大脑的微观组织层组成,包含循环的脊髓液。癌细胞扩散到软脑膜间隙或软脑膜转移(LM)是癌症的致命并发症,最常见
英文摘要
The leptomeninges consist of microscopic tissue layers that cover the brain and contain the circulating spinal fluid. The spread of cancer cells into the leptomeningeal space or leptomeningeal metastasis (LM) is a fatal complication of cancer, most common
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会议论文
Characterizing the role of Wnt signaling in human medulloblastoma stem cells
  • 批准号:
    224327
  • 项目类别:
    Studentship Programs
  • 资助金额:
    $1.27万
  • 财政年份:
    2011
  • 负责人:
    Manoranjan Branavan
  • 依托单位:
In vivo clonal evolution of medulloblastoma brain tumour-initiating cells in response to therapy: Discovering the refractory brain tumour-initiating cell population
  • 批准号:
    247898
  • 项目类别:
    Studentship Programs
  • 资助金额:
    $10.93万
  • 财政年份:
    2011
  • 负责人:
    Manoranjan Branavan
  • 依托单位:
海外基金