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In vivo clonal evolution of medulloblastoma brain tumour-initiating cells in response to therapy: Discovering the refractory brain tumour-initiating cell population

In vivo clonal evolution of medulloblastoma brain tumour-initiating cells in response to therapy: Discovering the refractory brain tumour-initiating cell population
髓母细胞瘤脑肿瘤起始细胞响应治疗的体内克隆进化：发现难治性脑肿瘤起始细胞群
批准号：
247898
负责人：
Manoranjan Branavan
金额：
$10.93万
依托单位：
McMaster University
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2011
资助国家：
加拿大
项目状态：
已结题
起止时间：
2011-11-01 至 2014-11-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=247898&lang=en
关键词：
Brain Tumour Initiating Cells Cancer Stem Cells Chemotherapy Ct-Pet Imaging Fluorescent-Activated Cell Sorting Human-Mouse Xenograft Model Lentiviruses Medulloblastoma Microarray Gene Expression Profiling Radiotherapy

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英文摘要
The Cancer Stem Cell (CSC) hypothesis suggests that tumours are organized into a hierarchy with a rare population of cells, termed CSCs, having the ability to initiate, proliferate, and maintain tumour growth. This is in sharp contrast to all other cells
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Characterizing the role of Wnt signaling in human medulloblastoma stem cells
  • 批准号：
    224327
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $1.27万
  • 财政年份：
    2011
  • 负责人：
    Manoranjan Branavan
  • 依托单位：
    McMaster University
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