Synthesis and Chemistry of Novel Fluorocarbons

这项研究的重点是合成和研究一系列高度氟化的目标分子的化学性质，所有这些目标分子的骨架都是12个或更少的碳原子。从头算量子力学计算将被用作实验设计的指导和实验结果解释的辅助。有了这个更新奖，合成有机项目正在支持达特茅斯学院化学系的大卫·m·勒马尔博士的研究。勒马尔教授将把他的工作重点放在一系列高氟化合物的合成和化学研究上。氟取代有机分子中的氢会导致性质和化学行为的巨大差异。因此，氟碳化学具有重要的商业意义。

The focus of this research entails the synthesis and investigation of the chemistry of an array of highly fluorinated target molecules, all of which have skeletons of twelve or fewer carbon atoms. Ab initio quantum mechanical calculations will be employed as both a guide to the design of experiments and as an aid in the interpretation of experimental results. With this renewal award, the Synthetic Organic Program is supporting the research of Dr. David M. Lemal of the Department of Chemistry at Dartmouth College. Professor Lemal will focus his work on the synthesis and investigation of the chemistry of an array of highly fluorinated compounds. Replacement of the hydrogens in organic molecules by fluorine results in dramatic differences in both properties and chemical behavior. As a result, fluorocarbon chemistry has great commercial importance.