A Program to Develop Isogenic and Congenic Lines of Hydractinia
开发水螅等基因和同系系的计划
基本信息
- 批准号:9531689
- 负责人:
- 金额:$ 4.97万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:1996
- 资助国家:美国
- 起止时间:1996-02-01 至 1998-01-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
; R o o t E n t r y F #( Y C o m p O b j b W o r d D o c u m e n t v O b j e c t P o o l #( Y #( Y 4 @ ! " # $ % & F Microsoft Word 6.0 Document MSWordDoc Word.Document.6 ; 9531689 Buss Invertebrate allorecognition responses have been known since the turn of the century and have been claimed to represent primitive vestiges of the vertebrate immune system. Several attempts have been made to establish the molecular basis of these responses, without notable success. This is due in part to lack of an adequate laboratory model system, particularly the lack of defined genetic lines bred for their fusibility characteristics. This project will continue efforts to develop isogenic and congenic lines of the hydrozoan Hydractinia symbiolongicarpus. These organisms would then be used in studies of allorecognition which will provide information not only on these organisms but on the origin of the immune response. *** ; Oh +' 0 $ H l D h R:\WWUSER\TEMPLATE\ABSTRACT.DOT 9531689 Barbara S u m m a r y I n f o r m a t i o n ( Zain Barbara Zain @ E Y @ @ E Y ( @ F # Microsoft Word 6.0 3 ; e = e v " " " " " " " L L L L L L V L k e ` d d d d d d d # - M T $ R k " d d d d d k d " " d ` d d d d " d " d 6 " " " " d d d 9531689 Buss Invertebrate allorecognition responses have been known since the turn of the century and have been claimed to represent primitive vestiges of the vertebrate immune system. Several attempts have been made to establish the molecular basis of these responses, without notable success. This is due in part to lack of an adequate laboratory model system, particularly the lack of defined genetic lines bred for their fusibility characteristics. This project will continue efforts to develop isogenic and congenic lines of the hydrozoan Hydractinia symbiolongicarpus. These organisms would then be used in studies of allorecognition which will provide information not only on these organisms but on the origin of the immune response. *** u $ $ $ $ $ $ $ $ $ $ $ $
;R o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o o4 @ !# $ % & F Microsoft Word 6.0 Document MSWordDoc。6;无脊椎动物异体识别反应自世纪之交以来就已被发现,并被认为代表了脊椎动物免疫系统的原始遗迹。已经进行了几次尝试来确定这些反应的分子基础,但没有取得显著的成功。这部分是由于缺乏适当的实验室模型系统,特别是缺乏根据其融合特性培育的确定的遗传系。本项目将继续努力开发共生水螅虫等基因系和同源系。这些生物体将被用于异体识别的研究,这将不仅提供有关这些生物体的信息,而且提供有关免疫反应起源的信息。*** ;# # # # # # # # # # # # # # # # # # # #[DOT 9531689]芭芭拉,你是我的妈妈,我是你的妈妈,我是你的妈妈。Zain芭芭拉Zain @ @ @ Zain @ @ @ f#微软Word 6.0;e = e v " " " " " " " L L L L L L L k V e ` d d d d d d d # - 米 T $ R k " d 维维 d d k d " " d‘ d d d ’ d ' d ' d ' d ' d ' d ' d ' d ' d ' d ' d ' d ' s无脊椎动物异体识别反应自世纪之交以来就已被发现,并被认为代表了脊椎动物免疫系统的原始遗迹。已经进行了几次尝试来确定这些反应的分子基础,但没有取得显著的成功。这部分是由于缺乏适当的实验室模型系统,特别是缺乏根据其融合特性培育的确定的遗传系。本项目将继续努力开发共生水螅虫等基因系和同源系。这些生物体将被用于异体识别的研究,这将不仅提供有关这些生物体的信息,而且提供有关免疫反应起源的信息。* * *U $ $ $ $ $ $ $ $ $ $ $ $
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Leo Buss其他文献
Leo Buss的其他文献
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{{ truncateString('Leo Buss', 18)}}的其他基金
CSBR: Natural History Collections: Cataloging and imaging the Yale Peabody Museum Invertebrate Zoology microscope slide collection
CSBR:自然历史收藏:耶鲁皮博迪博物馆无脊椎动物学显微镜幻灯片收藏的编目和成像
- 批准号:
1349111 - 财政年份:2014
- 资助金额:
$ 4.97万 - 项目类别:
Continuing Grant
CSBR: Natural History Collections: Curatorial upgrade and database development of the former George Gray Museum
CSBR:自然历史收藏:前乔治·格雷博物馆的策展升级和数据库开发
- 批准号:
1203483 - 财政年份:2012
- 资助金额:
$ 4.97万 - 项目类别:
Standard Grant
Evolutionary Genetics of Hydroid Allorecognition
水螅同种异体识别的进化遗传学
- 批准号:
0818295 - 财政年份:2008
- 资助金额:
$ 4.97万 - 项目类别:
Continuing Grant
Transfer to a New Facility, Curatorial Upgrade, and Augmenting of an Online Database of the Peabody Museum's Invertebrate Zoology Fluid-Preserved Collection
皮博迪博物馆无脊椎动物学液体保存藏品转移到新设施、策展升级和在线数据库扩充
- 批准号:
0646427 - 财政年份:2007
- 资助金额:
$ 4.97万 - 项目类别:
Continuing Grant
BE/GEN-EN: A Genomic Approach to Physiological Tolerance, Adaptation and Dispersal
BE/GEN-EN:生理耐受性、适应和传播的基因组方法
- 批准号:
0319076 - 财政年份:2003
- 资助金额:
$ 4.97万 - 项目类别:
Continuing Grant
Fine Structure Genetic and Molecular Characterization of a Primitive Allorecognition Locus
原始同种异体识别基因座的精细结构遗传和分子特征
- 批准号:
9817380 - 财政年份:1999
- 资助金额:
$ 4.97万 - 项目类别:
Standard Grant
ABR: Colony Integration in the Clonal Marine Benthos
ABR:克隆海洋底栖动物的群体整合
- 批准号:
9315082 - 财政年份:1994
- 资助金额:
$ 4.97万 - 项目类别:
Continuing Grant
Dissertation Research: Molecular Systematics of Orb-Web Weaving Spiders
论文研究:球网蜘蛛的分子系统学
- 批准号:
9321548 - 财政年份:1994
- 资助金额:
$ 4.97万 - 项目类别:
Standard Grant
SGER: Dynamics of Cnidarian Vascular Systems
SGER:刺胞动物血管系统动力学
- 批准号:
9215183 - 财政年份:1992
- 资助金额:
$ 4.97万 - 项目类别:
Standard Grant
Use of the Homeobox System to Elucidate Metazoan Sister-Group Relationships
使用同源框系统阐明后生动物姐妹群关系
- 批准号:
9119437 - 财政年份:1992
- 资助金额:
$ 4.97万 - 项目类别:
Continuing Grant
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