Integrating Laser Spectroscopic Studies in Biophysical Chemistry into Advanced Undergraduate Laboratory Courses

将生物物理化学中的激光光谱研究纳入高级本科实验室课程

• 批准号: 9550822
• 负责人: Colleen Jones
• 金额: $ 3.43万
• 依托单位: University of South Alabama
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-07-01 至 1998-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9550822&HistoricalAwards=false
• 关键词: Integrating; Laser; Spectroscopic; Studies; Biophysical

The department is constructing a time-resolved fluorescence spectrophotometer for use in advanced undergraduate laboratory courses. The main activities of the project are (1) enhancing and modernizing the spectroscopy component in advanced undergraduate laboratories by the introduction of lasers; (2) using fluorescence spectroscopy as a tool to expose students to current research interests in biophysical chemistry; (3) collecting data to reinforce chemical principles introduced in the courses; and (4) providing students with training in techniques for both the physical-chemical characterization and dynamical study of biomolecules. The chosen set of experiments uses time-resolved laser fluorescence spectroscopic techniques for data collection and exposes students to research on antibodies, nucleic acids, and heme proteins, and to the dynamical processes occurring in biomolecules. The experiments also introduce the fundamentals of fluorescence spectroscopy as well as exposing students to modern techniques in pulsed laser spectroscopy.

该系正在建造一个时间分辨荧光分光光度计，用于高级本科实验室课程。 该项目的主要活动是：（1）通过引入激光，加强和更新高等本科实验室的光谱学部分;（2）利用荧光光谱学作为一种工具，使学生接触到当前生物物理化学的研究兴趣;（3）收集数据，加强课程中介绍的化学原理;（4）培养学生掌握生物分子的物理化学表征和动力学研究的技术。 所选的一组实验使用时间分辨激光荧光光谱技术进行数据收集，并使学生了解抗体，核酸和血红素蛋白的研究，以及生物分子中发生的动态过程。 实验还介绍了荧光光谱学的基本原理，并让学生接触到脉冲激光光谱学的现代技术。