Modern Applications of Separation Science in the Undergraduate Curriculum

分离科学在本科课程中的现代应用

• 批准号: 9551840
• 负责人: Michael Burke
• 金额: $ 4.13万
• 依托单位: University of Arizona
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-05-01 至 1997-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9551840&HistoricalAwards=false
• 关键词: Modern; Applications; Separation; Science; Undergraduate

This project is developing a program to incorporate modern applications of separation science in the undergraduate curriculum. This includes the acquisition of new capillary electrophoresis (CE) instrumentation and new liquid chromatography (HPLC) capabilities, to continue the upgrade of analytical instrumentation in the teaching program. New experiments are being developed, along the following lines, for students at the junior and senior levels: (a) CE separation and quantitation of biologically significant molecules of high molecular weight (the instrumentation also provides students with their first exposure to analysis with nanogram sample quantities); (b) separation and quantitation of pharmaceutical compounds by liquid chromatography (photodiode array detection allows students to carry out peak purity analysis); and (c) optimization of solvent composition and flow rate in LC to determine the C60/C70 ratio in locally produced fullerene samples. This program allows for the continued development of new experiments, designed to target the fastest growing segment of our student population the life sciences oriented students.

该项目正在开发一项计划，将分离科学的现代应用纳入本科课程。这包括购买新的毛细管电泳仪(CE)和新的液相色谱(HPLC)功能，以继续升级教学计划中的分析仪器。正在为初级和高级学生开展以下新的实验：(A)毛细管电泳法分离和定量具有生物意义的高分子量分子(该仪器还为学生提供了首次接触到纳克样品量的分析机会)；(B)用液相色谱分离和定量药物化合物(光电二极管阵列检测使学生能够进行峰纯度分析)；(C)优化LC的溶剂组成和流动速度，以确定本地生产的富勒烯样品中的C60/C70比率。该计划允许继续开发新的实验，旨在针对我们学生群体中增长最快的部分--面向生命科学的学生。